Lynch, Eilish M. and McGee, Mark and Doyle, Sean and Earley, Bernadette
Effect of pre-weaning concentrate
supplementation on peripheral distribution of
leukocytes, functional activity of neutrophils,
acute phase protein and behavioural responses
of abruptly weaned and housed beef calves.
BMC Veterinary Research, 8 (1).
Background: The effect of pre-weaning concentrate supplementation on peripheral distribution of leukocytes,
functional activity of neutrophils, acute phase protein response, metabolic and behavioural response, and
performance of abruptly weaned and housed beef calves was investigated. Calves were grazed with their dams
until the end of the grazing season when they were weaned and housed (day (d) 0) in a concrete slatted floor
shed, and offered grass silage ad libitum plus supplementary concentrates. Twenty-six days prior to weaning and
housing, 20 singled suckled, pure-bred Simmental male (non-castrated), (n = 10, m) and female (n = 10, f) calves
were assigned to one of two treatments (i) concentrate supplement (CS: n = 10 (5 m and 5 f), mean age (s.d.) 201
(12.8) d, mean weight (s.d.) 258 (20.2) kg) or (ii) no concentrate supplement (controls) (NCS: n = 10, (5 m and 5 f),
mean age (s.d.) 201 (13.4) d, mean weight (s.d.) 257 (19.6) kg) pre-weaning.
Results: There was a treatment × sampling time interaction (P < 0.05) for percentage CD4+ and WC1+ (gδ T cells)
lymphocytes and concentration of plasma globulin. On d 2, percentage CD4+ lymphocytes decreased (P < 0.001)
in both treatments. Subsequently on d 7, percentage of CD4+ lymphocytes increased (P < 0.01) in CS compared
with d 0, whereas percentage of CD4+ lymphocytes in NCS did not differ (P > 0.05) from d 0. On d 2, WC1+
lymphocytes decreased (P < 0.05) in both treatments but the decrease was greater (P <0.05) in NCS than CS.
Subsequently, percentages did not differ (P > 0.05) from pre-weaning baseline. On d 2, the increase in
concentration of globulin was greater (P < 0.05) in CS compared with NCS, and subsequently there was no
difference between treatments. Pre-weaning ADG was 1.07 (s.e.m.) (0.26) kg and 0.99 (s.e.m.) (0.26) kg for CS and
NCS, respectively. Post-weaning, CS calves spent more time lying compared with NCS calves.
Conclusions: Calves supplemented with concentrate prior to weaning had a lesser reduction in WC1+
lymphocytes, increased percentage CD4+ lymphocytes and concentration of total protein, and spent more time
lying post-weaning, compared with non-supplemented calves.
||leukocytes; functional activity of neutrophils; acute phase protein; behavioural responses of abruptly weaned and housed beef calves;
||Faculty of Science and Engineering > Biology
Dr. Sean Doyle
||28 Feb 2012 15:43
|Journal or Publication Title:
||BMC Veterinary Research
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