Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) 4th meeting: Lessons learned from first clinical trials


Franquesa, Marcella and Hoogduijn, Martin J. and Reinders, Marlies E. and Eggenhofer, Elke and Engela, Anja U. and Mensah, Fane K. and Torras, Joan and Pileggi, Antonello and van Kooten, Cees and Mahon, Bernard P. and Detry, Oliver and Popp, Felix C. and Benseler, Volker and Casiraghi, Federica and Johnson, Christian and Ancans, Janis and Fillenberg, Barbara and delaRosa, Olga and Aran, Josep M. and Roemeling-van Rhijn, Marieke and Pinxteren, Jef and Perico, Norberto and Gotti, Eliana and Christ, Bruno and Reading, James and Introna, Martino and Deans, Robert and Shagidulin, Murat and Farré, Ramon and Rambaldi, Alessandro and Sanchez-Fueyo, Albert and Obermajer, Natasha and Pulin, Audrey and Dor, Frank J.M.F. and Portero-Sanchez, Isabel and Baan, Carla C. and Rabelink, Ton J. and Remuzzi, Giuseppe and Betjes, Michiel G.H. and Dahlke, Marc H. and Grinyó, Josep M. (2013) Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) 4th meeting: Lessons learned from first clinical trials. Transplantation, 96 (3). pp. 234-238. ISSN 0041-1337

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Abstract

The 4th expert meeting of the MiSOT (Mesenchymal Stem Cells in Solid Organ Transplantation) Consortium took place in Barcelona on the 19th and 20th of October 2012. This meeting focused on the translation of pre-clinical data into early clinical settings. This position paper highlights the main topics explored on the safety and efficacy of mesenchymal stem cells (MSC) as a therapeutic agent in solid organ transplantation and emphasizes the issues (proper timing, concomitant immunossupression, source and immunogenicity of MSC and oncogenicity) that have been addressed and will be followed up by the MiSOT Consortium in future studies.

Item Type: Article
Keywords: MiSOT Study Group; MiSOT Consortium; Mesenchymal Stem Cells; Transplantation; Immunomodulation; Position paper;
Academic Unit: Faculty of Science and Engineering > Biology
Item ID: 7152
Identification Number: 10.1097/TP.0b013e318298f9fa
Depositing User: Bernard Mahon
Date Deposited: 01 Jul 2016 16:16
Journal or Publication Title: Transplantation
Publisher: Lippincott, Williams & Wilkins
Refereed: Yes
URI:

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