Neurospora crassa ve-1 affects asexual conidiation


Bayram, Ozgur and Krappmann, Sven and Seiler, Stephan and Vogt, Nico and Braus, Gerhard H. (2008) Neurospora crassa ve-1 affects asexual conidiation. Fungal Genetics and Biology, 45 (2). pp. 127-138. ISSN 1087-1845

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Abstract

The velvet factor of the homothallic fungus Aspergillus nidulans promotes sexual fruiting body formation. The encoding veA gene is conserved among fungi, including the ascomycete Neurospora crassa. There, the orthologous ve-1 gene encodes a deduced protein with high similarity to A. nidulans VeA. Cross-complementation experiments suggest that both the promoter and the coding sequence of N. crassa ve-1 are functional to complement the phenotype of an A. nidulans deletion mutant. Moreover, ve-1 expression in the heterologous host A. nidulans results in development of reproductive structures in a light-dependent manner, promoting sexual development in the darkness while stimulating asexual sporulation under illumination. Deletion of the N. crassa ve-1 locus by homologous gene replacement causes formation of shortened aerial hyphae accompanied by a significant increase in asexual conidiation, which is not light-dependent. Our data suggest that the conserved velvet proteins of A. nidulans and N. crassa exhibit both similar and different functions to influence development of these two ascomycetes.

Item Type: Article
Additional Information: The definitive version of this article is available at DOI: 10.1016/j.fgb.2007.06.001
Keywords: Ascomycete; Conidiation; Fruiting body; Velvet;
Academic Unit: Faculty of Science and Engineering > Biology
Item ID: 7184
Identification Number: 10.1016/j.fgb.2007.06.001
Depositing User: Ozgur Bayram
Date Deposited: 13 Jul 2016 13:52
Journal or Publication Title: Fungal Genetics and Biology
Publisher: Elsevier
Refereed: Yes
URI:

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