Braus, Gerhard H. and Irniger, Stefan and Bayram, Ozgur
(2010)
Fungal development and the COP9 signalosome.
Current Opinion in Microbiology, 13 (6).
pp. 672-676.
ISSN 1369-5274
Abstract
The conserved COP9 signalosome (CSN) multiprotein complex
is located at the interface between cellular signaling, protein
modification, life span and the development of multicellular
organisms. CSN is required for light-controlled responses in
filamentous fungi. This includes the circadian rhythm of
Neurospora crassa
or the repression of sexual development by
light in
Aspergillus nidulans
. In contrast to plants and animals,
CSN is not essential for fungal viability. Therefore fungi are
suitable models to study CSN composition, activity and cellular
functions and its role in light controlled development.
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