Fungal development and the COP9 signalosome

Braus, Gerhard H. and Irniger, Stefan and Bayram, Ozgur (2010) Fungal development and the COP9 signalosome. Current Opinion in Microbiology, 13 (6). pp. 672-676. ISSN 1369-5274

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The conserved COP9 signalosome (CSN) multiprotein complex is located at the interface between cellular signaling, protein modification, life span and the development of multicellular organisms. CSN is required for light-controlled responses in filamentous fungi. This includes the circadian rhythm of Neurospora crassa or the repression of sexual development by light in Aspergillus nidulans . In contrast to plants and animals, CSN is not essential for fungal viability. Therefore fungi are suitable models to study CSN composition, activity and cellular functions and its role in light controlled development.

Item Type: Article
Keywords: Fungal development; COP9 signalosome;
Academic Unit: Faculty of Science and Engineering > Biology
Faculty of Science and Engineering > Research Institutes > Institute of Immunology
Item ID: 8154
Identification Number: 10.1016/j.mib.2010.09.011
Depositing User: Ozgur Bayram
Date Deposited: 12 Apr 2017 11:05
Journal or Publication Title: Current Opinion in Microbiology
Publisher: Elsevier
Refereed: Yes

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